Epoxy-α-Lapachone Has In Vitro and In Vivo Anti-Leishmania (Leishmania) amazonensis Effects and Inhibits Serine Proteinase Activity in This Parasite

Título:

Epoxy-α-Lapachone Has In Vitro and In Vivo Anti-Leishmania (Leishmania) amazonensis Effects and Inhibits Serine Proteinase Activity in This Parasite

Autor:

Saulo Cabral Bourguignon

Ano:

2015

DOI:

10.1128/aac.04742-14

Revista:

Antimicrobial Agents and Chemotherapy (Print)

ISSN:

00664804

Tags:

serine proteinase

Idioma:

Português

Buscar essa publicação no Google Acadêmico

Publicações com a mesma autoria

Current understanding of Dendritic cells and their co-stimulatory molecules as a key in generating efficient T cell responses in Lepromatous Leprosy

Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound

Heme metabolism as a therapeutic target against protozoan parasites

BJ-48, a novel thrombin-like enzyme from the Bothrops jararacussu venom with high selectivity for Arg over Lys in P1: Role of N-glycosylation in thermostability and active site accessibility.

Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2--oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment

The momgolian gerbil , Meriones unguiculatus (Rodentia: Cricetidae): A suitable host for species of New Word Leishmaniae.

DNA methylation: A promising target for the twenty-first century

Potency evaluation of antivenoms in Brazil: The national control laboratory experience between 2000 and 2006

The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis

Detrimental effect of Nitric oxide on Trypanosoma cruzi and Leishmania major-like cells